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Doctor Who Fandom Curse:
Knowing that at some point your Doctor will have to regenerate.
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Supernatural Fandom Curse:
Knowing that your Series will end.... and soon.
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Avengers Fandom Curse:
Knowing that Joss Whedon will likely kill a favorite character.
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Twilight Fandom Curse:
Knowing that you will never win a fight against another fandom.... ever.
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Harry Potter Fandom Curse:
Knowing that it will never be as good as the first time around.
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Sherlock Fandom Curse:
Knowing that after waiting forever you will probably only get three more episodes with a cliff hanger even worse than the previous one.
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Queer as Folk Fandom Curse:
Knowing that it's only time...and there won't be another episode to repair the damage done by the finale.
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Glee Fandom Curse:
The show
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Lost Fandom Curse:
Knowing that you will never know what really happened to all the characters.
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The Whedonite Fandom:
Knowing that Joss Whedon will kill ALL of your favorite characters, bring them back, and kill them some more just for the hell of it.
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Torchwood Fandom Curse:
Miracle Day.
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John Barrowman / Scott Gill Fandome Curse:
No fanfiction what so ever.